Oral viral infections
This review article describes some common intraoral viral infec-tions general dentists may encounter in their daily clinical practise. Infections with the herpes simplex virus often have an acute char-acter with a biphasic natural course. The infection often makes its first appearance with pain and it is important to distinguish this from dental instigated pain. The clinical picture varies but has mul-tiple vesicles as key features. Treatment with antiviral agents may arise in difficult cases, if so the start of treatment is crucial. Unlike herpes simplex infections, human papilloma virus infections are essentially asymptomatic. They also have a more wart-like growth pattern. The high frequency of human papillomaviruses in premalignant condition and in certain types of oral cancer indicates association with these different forms of oral mucosal lesions. It is unclear, however, if human papilloma virus infection is a significant risk factor for developing oral cancer. Treatment of human papil-loma virus-induced oral mucosal lesions is surgical.
Coxsackie viruses can give rise to so-called autumn blisters, in English is known as hand, foot and mouth disease. It is a mild disease that usually affects children under 10 years of age, though adults can become affected also. Prodromal symptoms are char-acterized by mild fever and malaise. Oral vesicles and desquama-tions follow shortly after. No specific treatment exists and sponta-neous healing is usually achieved within 1-2 weeks.